Manifestation tip 3: ask the source
If you believe the universe is conspiring against you, then one of three things is happening.
The universe is conspiring against you because you think the universe is conspiring against you.
The universe is not conspiring against you and you are misinterpreting circumstances either:
not seeing how your decisions and actions directly led to what you are experiencing, or
reading too much into phenomena because you have a scarcity mindset and can't see how these things have a high likelihood of occurrence for anyone (not just you).
The universe is conspiring against you in order to force you to ask "is the universe conspiring against me" which increases your consciousness, particularly your spiritual awareness.
In each of these cases you have assumed that there exists some force that has the ability to — and apparently interest in — influencing circumstances in your life.
Since you believe that, then why don't you petition this force directly through prayer or whatever means you feel comfortable with it?
Inquire about its intentions. Ask it what it wants you to know, do, learn or change in order to improve circumstances in your life.
Because if the universe is actually conspiring against you then what you are experiencing is not random but for a reason — and going directly to the source is the best way to find out what that reason is.